Will you use PureOS or another distro?

Yes, but I want to use it for backup and recovery, so it needs to work in scenarios where the eMMC disk is not bootable because someone has hosed it (i.e. disk hardware functioning but content not usable).

A USB disk connected via the USB-C port (with adapter if necessary) would be an alternative to booting from µSD card.

Booting from µSD card has been discussed inconclusively before: