@weirdnerd as your question is unrelated to the thread you asked it in, consider this thread a gift for such a discussion.
Realistically qubes is built around the x86 ecosystem and I don’t see it being ported to arm anytime soon, but in the event it were ported I could see Purism offering it as an option.
I suppose a slightly obvious preliminary question to ask in relation to this is: Do the CPU cores in the Librem 5 actually have any virtualisation features?
This seems like something that would probably not be too difficult to answer by digging through datasheets, but I won’t be the one to put in the work.