After closing the lid and waking from suspend, performance is noticeably affected.
Video playback becomes choppy. Restarting any Qubes involved does not help.
Have also been following this guide on how to disable throttling and generally improve performance with tools such as cpupower.
By the way, i not recommend to disable power limit forever. It good for performance, but can cause problems when running on baterry. Also, in long tasks CPU need to drop frequency anyway, because cooling solution is not capable to dissipate 25 watts.
About suspend, check this topic. I personally recommend to check that you don’t plug ang unplug USB devices when lid closed, it helped me with this issue.